Speaking about the breakthrough, Prof Das said, “This work exemplifies how scientific innovation can directly address the pressing needs of cancer treatment. The hydrogel’s unique properties allow it to work in harmony with the biological environment, offering precision where it is needed most. We are excited by its potential to transform our thoughts about localized drug delivery.”In pre-clinical trials on a murine model of breast cancer, the hydrogel showcased remarkable efficacy. A single injection of the hydrogel, loaded with the chemotherapy drug doxorubicin, resulted in a 75% reduction in tumour size within 18 days. Crucially, the hydrogel remained localized at the tumour site, steadily releasing the drug over time without causing detectable side effects on other organs, the IIT Guwahati said.“This innovative delivery system enhances the drug’s effectiveness while reducing the required dosage, thus minimizing toxicity. Laboratory studies further demonstrated that the hydrogel improves drug uptake by cancer cells, induces cell cycle arrest, and promotes programmed cell death, thereby attacking tumours on multiple fronts,” the institute further stated.
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